Ameloblastoma is a rare, noncancerous (benign) tumor that develops most often in the jaw near the molars. Ameloblastoma begins in the cells that form the protective enamel lining on your teeth.
The most common type of ameloblastoma is aggressive, forming a large tumor and growing into the jawbone. Treatment may include surgery and radiation. In some cases, reconstruction may be necessary to restore your teeth, jaw and facial appearance. Some types of ameloblastoma are less aggressive.
Causes
Injury
An injury to your jaw or an infection in your mouth also might raise your risk.
Lack of protein
Scientists think some viruses or a lack of protein or minerals in your diet may be linked to them as well.
Genetics mutations
Recent studies show that many people with ameloblastoma have common genetic mutations associated with cell division problems that fuel tumor growth. Mutations involving the BRAF and SMO genes are common with ameloblastomas.
Targeted therapy
Experts are currently researching these mutations to identify treatments that target the abnormal cell changes (targeted therapy) and destroy tumor-causing cells.
And finally, Rarely, ameloblastoma can become cancerous (malignant). Very rarely, ameloblastoma cells can spread to other areas of the body (metastasize), such as the lymph nodes in the neck and lungs. Ameloblastoma may recur after treatment always contact your Healthcare provider for proper diagnosis and treatment. All information gotten from Mayo clinic.
